Flop21
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- May 12, 2013
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- HSC
- 2015
Kidney disease is the 8th leading cause of death in the United States. An estimated 31 million people in the United States (10% of the population) have chronic kidney disease (CKD). CKD is more common among women, but men with CKD are 50% more likely than women to progress to kidney failure (also called end-stage renal disease or ESRD).
Renal dialysis or kidney transplants can be used to treat CKD. Discuss issues associated with both treatments. (5 marks)
Renal dialysis involves cleaning the blood by passing it through a semi-permeable tube, surrounded by dialysis solution, so wastes diffuse out. This process needs to be done 3 times a week, 4-5 hours at a time. It can be dangerous due to the anti-clotting agent added to the clean blood, risk of infection and damage to blood cells passing through the tubing. Also, nutrients cannot be selectively reabsorbed, but are lost, as well as water.
A kidney transplant also has possible issues. When an organ transplant occurs, the body recognises the tissue as foreign and thus attacks the organ. Immunosupressive drugs are therefore needed to suppress the immune system, however this makes the patient more vulnerable to complications from pathogens, such as the common cold. Even so, the body still may reject the organ and destroy it; a deadly complication. The organ therefore needs to be closely matched as possible to the receiver's MHCI molecules(is this correct? otherwise what would I say here). Additionally, there may not be a kidney available and long waiting lists, especially due to the necessity for a close matched organ. The risks of surgery are also a possible issue, such as infection, complications, and blood loss.