info on this dot point (1 Viewer)

[massimo857]

hey i was woundering if i could get some help on this dot point, its realy bugging me

# use available evidence to analyse the links between gene expression and maintenance and repair of body tissue

thanx .....

 

[xiao1985]

lolz... i remember this one is one of the dodgy dp which i haven't properly being taught...

anywayz, cells' activity is under the correct expression of genes to perform repair, reproduce and growth. correct expression of genes will replace old cells, repair damaged cells and allow the maturation of cells in a natural process...

when genes are expressed incorrectly however, say the reproduce function is irregular, cells may undergo uncontrolled mitosis, which woudl be termed disease - cancer....

proto - onco genese, if i am not wrong =) is the one responsible for cell division =)

 

[massimo857]

thanx heaps,,,,i kinda get it now....do u know any good infectious diseases to study,,,that are realy interesting?

 

[babydoll_]

Malaria is interesting but that's already in the syllabus....

You could talk about AIDS... how the origins are unknown.. and it was spread mainly through infected blood transfusions and unprotected sexual contact... and how better hygiene and sexual practises have lead to a drop in the growth rate

 

[MaryTylerMoore]

Hey ,

In this assignment you need to refer to genes being the unit of inheritance, genes that unzip and produce mRNA, tRNA, polypeptides and then proteins of all different kinds (structural, catalytic, immunological to name a few).

Gene expression is the transfer of information from a gene to produce a protein or RNA.

Maintenance - Enzymes are proteins. Your body is maintained by enzymes. Also, genes code for the production of new cells. You could say how bones are replaced every 10 years or so in their entirety, and how many hndreds of thousands of blood cells die every second and are replaced by new ones, how skin cells fall off and are replaced by the genetic code which produces new proteins.

Repair - New structural proteins are produced from the genetic infromation in cells. After a cut, division occurs and new cells form which become specialised.

As mentioned, talk about proto-oncogenes, the p53 gene, the tumour supressor gene, CDK and cyclin (the last two aren't mentioned in the text book).

"CDK and cyclin are key molecules that control and coordinate DNA-synthesis, chromosome separation and cell division. CDK and cyclin together drive the cell from one cell cycle phase to the next.


Maybe check out:
US National Health Museum
http://www.accessexcellence.org/AB/GG/protein_synthesis.html
http://www.accessexcellence.org/AB/GG/steps_to_Prot.html

 

[xiao1985]

uhm... that's alot out of syllabus i think... i think the syllabus only require us to know how gene's can produce exact copies of cells to replace the old one's... even proto-onco gene is abit tangential to this dp i think...

 

[cko]

Originally posted by MaryTylerMoore
Hey ,

In this experiment you need to refer to genes being the unit of inheritance, genes that unzip and produce mRNA, tRNA, polypeptides and then proteins of all different kinds (structural, catalytic, immunological to name a few).

i didn't think that this was an experiement...

 

[t-i-m-m-y]

proto-onco rocks

basically, u need to draw the links between gene expresion and repair & maintenance of body tissues (haha i just restated the dot point---> then come up with specific stuff like mary said above

 

[TheKing]

Originally posted by babydoll_
Malaria is interesting but that's already in the syllabus....

You could talk about AIDS... how the origins are unknown.. nd it was spread mainly through infected blood transfusions and unprotected sexual contact... and how better hygiene and sexual practises have lead to a drop in the growth rate

A bit of interesting contreversy, some people believe that the AIDS virus actually came from monkeys. There are two theories about this, one is more fun than the other:
1. The first Polio vaccines were acutally made from ground up monkey livers or something along thoses lines and it got passed onto humans through that.
2. or, simply that so guy/girl had sex with a monkey and contracted the monkey virus.

 

[malkin86]

http://www.avert.org/origins.htm

The origins of AIDS, as according to a NGO that deals with AIDS.

 

[TheKing]

Originally posted by malkin86
http://www.avert.org/origins.htm

The origins of AIDS, as according to a NGO that deals with AIDS.

It is now generally accepted that HIV is a descendant of simian (monkey) immunodeficiency virus (SIV). Certain simian immunodeficiency viruses bear a very close resemblance to HIV-1 and HIV-2, the two types of HIV.


that came from the website.... see my little bit of info does have fact behind it....

and for those not so knowledgable people out there... NGO stands for Non Government Organisation

 

[cko]

ummm..... say u wr explaining this gene expression dot pt to someone INCREDIBLY stoopid.... how wud u explain it? cuz umm... i thought i was startn to get it till u all driftd off to malaria n HIV....=S

 

[TheKing]

heh... your not stupid, we're just idiots who like queer facts....

um sorry but are you sure that its in this topic?
if it is can u tell me where. like what point
i need to look at the other ones to see the context in which it is asked and then hopefully i can help you

 

[malkin86]

Each different gene in DNA codes for a particular polypeptide chain, which makes a protein. Proteins include enzymes (for metabolism), muscles and antibodies (I think).

Can you see how if a gene's expression is changed, the polypeptide chain is changed, so the enzyme, muscle, or antibody is changed?

For example, in Cystic Fibrosis, there are two alleles of a recessive gene that causes there to be no 'gateways' for salt to pass through the lung's cellular membrane, (and therefore water), thus stuffing up the whole homeostatic process.

 

[cko]

ok ok i think im startn to get it now... but then how come ppl startd refering to AIDS and malaria? i thought that it was a diff dot pt? n what's up with that proto onco gene?

 

[TheKing]

AIDS interferrs with the job of helper T-cells( i think)

i dunno
but proto onco gene basically controlls mitosis.... starts and stops cell division

 

[xiao1985]

Originally posted by TheKing

that came from the website.... see my little bit of info does have fact behind it....

no one really doubted you, theking =)

 

[xiao1985]

Originally posted by TheKing
AIDS interferrs with the job of helper T-cells( i think)

i dunno
but proto onco gene basically controlls mitosis.... starts and stops cell division

yes in deed aids interferes with the job of helper t cells...

protocogene is responsible for the cell growth part. tumour suppressor gene is responsible for controlling/counteracting the growth of cells. so when tumour occurs, the expression of tumour suppressor gene is inadaquate, hence the cells multiply uncontrolably...

 

[malkin86]

cos theyre interesting infectious diseases, which is a different dot point.

 

[TheKing]

Originally posted by xiao1985
no one really ever doubts you, theking =)

yes i think that all will agree
when i say that i am "THE KING"