Survivor39
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But why is it only toxic to bacteria??Budz said:I am also only guessing but isnt it because it is only toxic to bacteriums. You could also ask why some antibiotices affect certain species of bacteria and other dont.
Yes, fungi do secrete chemicals which inhibit bacterial growth. That was how penicillin was discovered. But how, that it only inhibit bacterial cells, not human cells??Budz said:I was always under the impression that some fungi secrete chemicals which were found to inhibit bacterial growth. After the testing upon various organisms it was concluded that only certain species of bacteria was affected by certain antibiotics.
NoBudz said:If no well my next best guess would be somethign to do with bacterium's lack of a nucleus. lol.
Not really.Budz said:And if not then i guess the antigens (chemical signature) of certain bacteria allow for attraction of ceratin antibiotics
The answer is that antibiotic attack bacteria mainly because of their cell walls, and their ribosomes.
Human cells do not consist a thick layer of cell walls. Bacteria do. Certain antibiotics target the cell walls because of their unique chemical structure. The bacterial cell wall is composed of layers of peptidoglycans, which crosslinks with each other via a chain amino acids. Therefore, antibiotics can:
Target peptidoglycan chain, OR
Target the crosslinks between the peptidoglycan, that is the amino acids.
But you might ask, why do antibiotics only target amino acids on bacteria? That is because we, humans have 20 amino acids, and bacteria have more than 20. Antibiotics target bacterial amino acids that do not exist in human, such as mesodiaminopimelic acid.
Hence cell wall is destroyed, bacteria burst and die. Examples of antibiotic that target cell walls - penicillin.
For ribosomes, bacteria have different ribosomal arrangement like 70S compared to human 80S which I dont want to go into too much detail to freak you out from doing science . Yeah, so antibiotic kill the 70S ribosomes and hence no protein synthesis, bacteria die. And plus, they could target bacterial amino acid on ribosomes as well.